Bioassays Based on Molecular Nanomechanics
نویسندگان
چکیده
منابع مشابه
Bioassays Based on Molecular Nanomechanics
Recent experiments have shown that when specific biomolecular interactions are confined to one surface of a microcantilever beam, changes in intermolecular nanomechanical forces provide sufficient differential torque to bend the cantilever beam. This has been used to detect single base pair mismatches during DNA hybridization, as well as prostate specific antigen (PSA) at concentrations and con...
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Molecular interaction is a key concept in our understanding of the biological mechanisms of life. Two physical properties change when one molecular partner binds to another. Firstly, the masses combine and secondly, the structure of at least one binding partner is altered, mechanically transducing the binding into subsequent biological reactions. Here we present a nanomechanical micro-array tec...
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ژورنال
عنوان ژورنال: Disease Markers
سال: 2002
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2002/856032